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Pain & Anxiety Relief: Fast-Acting for Better Care

March 2025 | IVPMED

Pain & Anxiety Formulations: Fast-Acting Relief through Mucosal Absorption

IVPMED’s platform enables fast-acting relief for pain, anxiety, and mood disorders through the precise delivery of nano-formulated active ingredients. These formulations are designed for rapid oral mucosal absorption, bypassing first-pass metabolism to provide faster onset and more predictable therapeutic outcomes. 

Our formulations are especially beneficial for:

  • Anxiety and panic attacks.

  • Chronic stress and depression.

  • Bipolar disorder symptom management.

  • Chronic and neuropathic pain.

Pain & Anxiety Relief: Fast-Acting for Better Care by IVPMED

Formulation & Mechanism

Each formulation contains Delta-8 THC and Melatonin, suspended in a water-based nanostructure. This allows the actives product to bind and pass through protein channels in the oral mucosa, ensuring rapid uptake directly into the bloodstream. 

Delivery is performed via the Slyder ultrasonic nebulizer adapter, designed for oral cavity targeting rather than pulmonary delivery. This method maximizes effect while reducing systemic side effects common with oral ingestion or intravenous administration.

Technical Details

How It’s Administered

  • Nebulizer adapter: Mesh size >6 micron @110kHz – 150 Khz.

  • Activation: User selects dose via touchscreen.

  • Inhalation process:

1. Inhale gently through mouthpiece.

2. The device vibrates twice for haptic feedback.

3. Mist is released directly into the oral cavity.

The mist adheres to oral membranes and is rapidly absorbed, enabling therapeutic effects within minutes — ideal for acute episodes of anxiety or breakthrough pain. 

Use Cases in Medical & Research Settings 

This formulation system is currently being evaluated for: 

  • Behavioral health clinics focused on rapid-onset interventions.

  • Pain management practices seeking safer alternatives to opioids.

  • Clinical trials testing cannabinoid-emulsified therapies.

  • At-home treatment programs under remote medical supervision.

Supporting Documentation

A downloadable technical PDF is attached here:

Active Pharmaceutical Ingredients (API) in Nanoform

It includes: 

  • Formulation composition.

  • Absorption profile.

  • Recommended use protocols.

  • References to ongoing clinical studies.

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